Title:- Single blind study of efficacy of Darvi Kashaya in Bahupitta
kamala with special reference to serum bilirubin levels.
Dr.
Mangesh Nalkande had submitted his dissertation to Pune University
in 2007 for the P.G. degree M.D. (Kaya Chikitsa). His guide was Dr. Sadanand V.
Deshpande & Research center was Tilak Ayurved Mahavidyalaya, Pune (M.S.)
India.
Dr.
Nalkande in his research work tried to assess efficacy of Darvi decoction
in Jaundice (Bahupitta) Kamala with special reference to serum bilirubin
levels. Darvi decoction was prepared as per textual reference.
For
the clinical trials study design was randomized single blind controlled. 40 patients
were included in study. Two groups of patients having bahupitta kamala were
prepared.
Group A -- was given Darvi
kashaya
Group B -- was given Erandapatra kashaya orally
Both in the dose of 60 ml. Time of administration of drug was 6to7a.m. Duration of
treatment was 21 days.
Assessment
was done with the help of subjective gradation of symptoms as follows- i) No symptoms = Nil/grade 0,
ii) Low symptoms
= grade 1,
iii)
Moderate symptoms = grade 2,
iv)
Severe symptoms = grade 3.
Objective criteria were
Serum Bilirubin, SGPT, and SGOT.
The study was concluded as follows –
Darvi kashaya 60 ml in the early morning with madhu for 3 weeks , was very effective in Bahupitta kamala ( Jaundice
) & reduces the serum bilirubin level within a shorter time period in
Bahupitta kamala.
Darvi
acts on liver cells detoxification of exogenous and endogenous toxins is done
by it. Dramatic reduction in hepatomegaly is observed. Darvi decoction taken in
excess quantity caused hrullasa & Chhardi.
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