Title:-Clinical assessment of Mahamanjishthadi ghanasar kalpa on mukhadushika
(Acne vulgaris).
Dr.
Bhaskar D. Date had submitted his dissertation to Pune University
in 1999. His guide was Prof. Dr. P. H. Kulkarni & Research center was Tilak
Ayurved Mahavidyalaya, Pune, (M.S.) India.
Dr.
Bhaskar Date in his research work tried to assess clinically effect of
Mahamanjishthadi ghanasar kalpa on Acne vulgaris.
For
the study Mahamanjishthadi ghanasar kalpa
was prepared with all 26 ingredients in equal proportion by weight & it was
prepared as mentioned in Bharat Bhaishya
Ratnakar . The drug was given in the dose of 2 tablets of 250 mg each = 500 mg three times a day, for 6 weeks = 42
days.
For
clinical study patients present with symptoms of Acne vulgaris but having other
dermatological or any other medical problem such as scabies, eczema were
excluded. 150 patients were selected randomly. The grouping of patients was as
follows. 200 patients were in pipeline.
a) Group 1 = 20
patients treated with placebo means tablets of sucrose.
b) Group 2 = 150
patients treated with Mahamanjishthadi ghanasar kalp.
Laboratory analysis of the drug showed that the drug sample, in the dosage of three tablets
to be having bacteriostatic affect
against the following bacteria namely Staphylococcus aureus, Escherichia coli, Pseudomonas acruginas and Proteus
mirabilis.
Clinical assessment was
done according severity of symptoms like discolouration, swelling and
distribution.
The study was concluded as follows-
Tab Mahamanjishthadi ghanasar kalpa,when
given in a dose of 2 Tab TDS for 6 weeks showed Good results in the patients of
Acne Vulgaris.
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